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SMG7 anticorps

SMG7 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7384099
  • Antigène Voir toutes SMG7 Anticorps
    SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
    Reactivité
    • 23
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 23
    Lapin
    Clonalité
    • 23
    Polyclonal
    Conjugué
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SMG7 est non-conjugé
    Application
    • 13
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human SMG7 (NP_963863.2).
    Isotype
    IgG
    Top Product
    Discover our top product SMG7 Anticorps primaire
  • Indications d'application
    WB 1:200-1:2000
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
    Autre désignation
    SMG7 (SMG7 Produits)
    Synonymes
    anticorps 9430023P16Rik, anticorps mKIAA0250, anticorps C1orf16, anticorps EST1C, anticorps SGA56M, anticorps Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), anticorps SMG7, nonsense mediated mRNA decay factor, anticorps Smg7, anticorps SMG7
    Sujet
    SMG7,C1orf16,EST1C,SGA56M,This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD), a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    Poids moléculaire

    Observed_MW: 127 kDa

    Calculated_MW: 122 kDa/127 kDa/131 kDa

    ID gène
    9887
    UniProt
    Q92540
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