ZNF451 anticorps

N° du produit ABIN7384122

Détail du produit anti-ZNF451 anticorps

Antigène: ZNF451 (Zinc Finger Protein 451 (ZNF451))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF451 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human ZNF451 (NP_001026794.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:200-1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ZNF451

Antigène: ZNF451 (Zinc Finger Protein 451 (ZNF451))

Autre désignation: ZNF451 (ZNF451 Produits)

Synonymes: anticorps COASTER, anticorps dJ417I1.1, anticorps 4930515K21Rik, anticorps 4933435G09Rik, anticorps AI596398, anticorps Kiaa0576-hp, anticorps Znf451, anticorps mKIAA1702, anticorps zinc finger protein 451, anticorps ZNF451, anticorps Zfp451

Sujet: ZNF451,COASTER,dJ417I1.1,E3 SUMO-protein ligase, has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation (By similarity). Has no activity with SUMO1 (PubMed:26524493). Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11' (PubMed:26524493). Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9'. Plays a role in regulating the transcription of AR targets.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 63 kDa/115 kDa/121 kDa

ID gène: 26036

UniProt: Q9Y4E5