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ALIX anticorps

PDCD6IP Reactivité: Humain, Rat, Hamster WB Hôte: Lapin Monoclonal R03-8C2 unconjugated
N° du produit ABIN7384341
  • Antigène Voir toutes ALIX (PDCD6IP) Anticorps
    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
    Reactivité
    • 75
    • 34
    • 31
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Hamster
    Hôte
    • 64
    • 13
    • 1
    Lapin
    Clonalité
    • 59
    • 18
    Monoclonal
    Conjugué
    • 32
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp ALIX est non-conjugé
    Application
    • 48
    • 26
    • 26
    • 21
    • 12
    • 12
    • 10
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity Purified
    Clone
    R03-8C2
    Isotype
    IgG
    Top Product
    Discover our top product PDCD6IP Anticorps primaire
  • Indications d'application
    WB 1:1000-1:2000
    Restrictions
    For Research Use only
  • Concentration
    300 μg/mL
    Buffer
    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
    Autre désignation
    ALIX (PDCD6IP Produits)
    Synonymes
    anticorps DDBDRAFT_0167145, anticorps DDBDRAFT_0185177, anticorps DDB_0167145, anticorps DDB_0185177, anticorps AIP1, anticorps ALIX, anticorps DRIP4, anticorps HP95, anticorps AI480591, anticorps AW544830, anticorps Aip1, anticorps Alix, anticorps C76364, anticorps Eig2, anticorps mKIAA1375, anticorps CG12876, anticorps DAIP1, anticorps Dmel\\CG12876, anticorps GB11744, anticorps RGD1561176, anticorps zgc:63638, anticorps wu:fb70d03, anticorps wu:fy65h02, anticorps PDCD6IP, anticorps aip1, anticorps alix, anticorps hp95, anticorps drip4, anticorps ALG-2 interacting protein X, anticorps programmed cell death 6 interacting protein, anticorps programmed cell death 6-interacting protein, anticorps Programmed cell death 6 interacting protein, anticorps programmed cell death 6 interacting protein L homeolog, anticorps alxA, anticorps PDCD6IP, anticorps Pdcd6ip, anticorps ALiX, anticorps LOC412662, anticorps pdcd6ip, anticorps Bm1_48390, anticorps pdcd6ip.L
    Sujet
    PDCD6IP,AIP1,ALIX,DRIP4,HP95,This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.
    Poids moléculaire

    Observed_MW: 96kDa

    Calculated_MW: 96kDa

    ID gène
    10015
    UniProt
    Q8WUM4
    Pathways
    Signalisation p53, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
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