GSDMD anticorps

N° du produit ABIN7384358

Détail du produit anti-GSDMD anticorps

Antigène: GSDMD (Gasdermin D (GSDMD))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp GSDMD est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity Purified

Clone: R06-5C5

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GSDMD

Antigène: GSDMD (Gasdermin D (GSDMD))

Autre désignation: GSDMD (GSDMD Produits)

Synonymes: anticorps GSDMDC1, anticorps GSDMD, anticorps DF5L, anticorps DFNA5L, anticorps 1810036L03Rik, anticorps AW558049, anticorps Dfna5l, anticorps Gsdmdc1, anticorps M2-4, anticorps gasdermin D, anticorps GSDMD, anticorps Gsdmd

Sujet: DF5L,DFNA5L,FKSG10,GSDMDC1,GSDMD,GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently,GSDMD is identified as a new component of inflammasomes,and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Poids moléculaire:

Observed_MW: 53kDa

Calculated_MW: 53kDa

ID gène: 79792

UniProt: P57764

Pathways: Inflammasome