CDC20 anticorps (AA 50-100)

N° du produit ABIN7448465

Détail du produit anti-CDC20 anticorps

Antigène: CDC20 (Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20))

Épitope: AA 50-100

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC20 est non-conjugé

Application: Immunohistochemistry (IHC)

Fonction: Rabbit anti-CDC20 IHC Antibody, Affinity Purified

Homologie: Dog,Horse,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Primates,Naked mole rat,Small-eared galago,Thirteen-lined ground squirrel,Crab-eating macaque,Northern white-cheeked gibbon,Chinese hamster

Purification: Affinity Purified

Immunogène: Between AA 50 and 100

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 500 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CDC20

Antigène: CDC20 (Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20))

Autre désignation: CDC20 (CDC20 Produits)

Sujet: Background: CDC20 is a WD repeat containing cell cycle-regulator that binds to and activates the ubiquitin-ligase activity of the APC/c (anaphase-promoting complex/cyclosome). APC/c ubiquitinating activity is responsible for the degradation of securin and cyclin B that prompts the onset of anaphase and exit from mitosis. CDC20 has also been reported to form a complex with histone deacetylases and can function as a transcriptional repressor involved in cell cycle arrest. As a regulator of APC/c activity, CDC20 plays a key role in the spindle-assembly checkpoint.

ID gène: 991

NCBI Accession: NP_001246

UniProt: Q12834