MAPKAP1 anticorps (C-Term)
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- Antigène Voir toutes MAPKAP1 Anticorps
- MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MAPKAP1 est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Fonction
- Rabbit anti-Sin1 IHC Antibody, Affinity Purified
- Homologie
- Rat,Chicken,Turkey,Sheep,Bovine,Dog,Horse,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Tasmanian devil,Crab-eating macaque,Zebra finch,Small-eared galago,Chinese hamster,Naked mole rat,Gray short-tailed opossum,Thirteen-lined ground squirrel,West Indian ocean coelacanth,Little brown bat,Duckbill platypus
- Purification
- Affinity Purified
- Immunogène
- Between AA 470 and C-term
- Isotype
- IgG
- Top Product
- Discover our top product MAPKAP1 Anticorps primaire
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- Indications d'application
- 1:100 - 1:500
- Restrictions
- For Research Use only
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- Concentration
- 100 μg/mL
- Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 12 months
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- Antigène
- MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))
- Autre désignation
- Sin1 (MAPKAP1 Produits)
- Synonymes
- anticorps CG10105, anticorps Dmel\\CG10105, anticorps dSin1, anticorps sin1, anticorps MAPKAP1, anticorps im:7143088, anticorps si:ch73-242f23.1, anticorps mip1, anticorps sin1b, anticorps sin1g, anticorps MGC53034, anticorps JC310, anticorps MIP1, anticorps SIN1, anticorps SIN1b, anticorps SIN1g, anticorps AI591529, anticorps D230039K05Rik, anticorps Sin1, anticorps SAPK-interacting protein 1, anticorps mitogen-activated protein kinase associated protein 1, anticorps mitogen-activated protein kinase associated protein 1 L homeolog, anticorps Sin1, anticorps MAPKAP1, anticorps mapkap1, anticorps Mapkap1, anticorps mapkap1.L
- Sujet
- Background: Stress-activated map kinase-interacting protein 1 (Sin1) is highly similar to the yeast stress- activated protein kinase SIN1. Sin1 is an essential mTORC2 subunit that is required to act as the PDK2 that phosphorylates Akt/PKB at Ser 473. Sin1 has been implicated as a scaffolding protein. Sin1 is required for rictor binding in the mTORC2 complex. Sin1 has also been shown to be important to the SAPK (stress-activated kinase) signaling pathway and in the nucleus may act as a scaffold between ATF-2 and p38 to facilitate p38-induced phosphorylation of ATF-2. Sin1 is also found to form a complex with c-Jun N-terminal kinase (JNK) and may similarly function as a scaffolding protein in JNK signaling.
- ID gène
- 79109
- NCBI Accession
- NP_001006618
- UniProt
- Q9BPZ7
- Pathways
- Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events
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