BRCAA1 anticorps (AA 125-175)

N° du produit ABIN7448931

Détail du produit anti-BRCAA1 anticorps

Antigène: BRCAA1 (ARID4B) (RBP1-like protein (ARID4B))

Épitope: AA 125-175

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRCAA1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Fonction: Rabbit anti-ARID4B IHC Antibody, Affinity Purified

Homologie: Mouse,Rat,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Green anole,Crab-eating macaque,Tasmanian devil,Thirteen-lined ground squirrel,Zebra finch,Little brown bat,Northern white-cheeked gibbon,Gray short-tailed opossum,Duckbill platypus,Naked mole rat,African elephant

Purification: Affinity Purified

Immunogène: Between AA 125 and 175

Isotype: IgG

Information d'application

Indications d'application:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur BRCAA1

Antigène: BRCAA1 (ARID4B) (RBP1-like protein (ARID4B))

Autre désignation: ARID4B (ARID4B Produits)

Sujet: Background: ARID4B (AT-rich interactive domain-containing protein 4B) is also known as RbBP1L1 (retinoblastoma binding protein 1-like 1) and is a retinoblastoma binding protein and member of the AT-rich interaction domain (ARID) family of proteins. In addition to the ARID DNA binding domain, ARID4B also contains a chromo domain and a TUDOR domain, indicating a function in chromatin organization and protein-protein interactions with methylated protein substrates. As a subunit of the SIN3A transcriptional co-repressor, ARID4B is implicated to be involved in chromatin remodeling and epigenetic modifications. ARID4B may play a role in the pathogenesis of breast cancer and other malignancies.

ID gène: 51742

NCBI Accession: NP_057458

UniProt: Q4LE39