UBR4 anticorps (AA 5133-5183)
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- Antigène Voir toutes UBR4 Anticorps
- UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
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Épitope
- AA 5133-5183
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp UBR4 est non-conjugé
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Application
- Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Fonction
- Rabbit anti-p600 IHC Antibody, Affinity Purified
- Homologie
- Mouse,Rat,Horse,Pig,Orangutan,Monkey,Gorilla,Chimpanzee,Little brown bat,Northern white-cheeked gibbon,White-tufted-ear marmoset
- Purification
- Affinity Purified
- Immunogène
- Between AA 5133 and 5183
- Isotype
- IgG
- Top Product
- Discover our top product UBR4 Anticorps primaire
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- Indications d'application
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IHC-IF: 1:50 - 1:500
IHC: 1:100 - 1:500
- Restrictions
- For Research Use only
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- Concentration
- 250 μg/mL
- Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 12 months
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- Antigène
- UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
- Autre désignation
- p600 (UBR4 Produits)
- Synonymes
- anticorps ZUBR1, anticorps RBAF600, anticorps p600, anticorps 1810009A16Rik, anticorps A930005E13Rik, anticorps D930005K06Rik, anticorps Gm1032, anticorps Gm1666, anticorps N28143, anticorps Zubr1, anticorps mKIAA0462, anticorps Rbaf600, anticorps ubiquitin protein ligase E3 component n-recognin 4, anticorps E3 ubiquitin-protein ligase UBR4, anticorps UBR4, anticorps Ubr4, anticorps LOC100511934
- Sujet
- Background: p600 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. It recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, p600 forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Additionally p600 regulates integrin-mediated signaling and may play a role in activation of FAK in response to cell-matrix interactions [taken from the Universal Protein Resource (UniProt) Q5T4S7].
- ID gène
- 23352
- NCBI Accession
- NP_065816
- UniProt
- Q5T4S7
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