UIMC1 anticorps (C-Term)

N° du produit ABIN7449010

Détail du produit anti-UIMC1 anticorps

Antigène: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UIMC1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Fonction: Rabbit anti-RAP80 IHC Antibody, Affinity Purified

Homologie: Gorilla

Purification: Affinity Purified

Immunogène: Between AA 650 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur UIMC1

Antigène: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Autre désignation: RAP80 (UIMC1 Produits)

Sujet: Background: RAP80 was first identified as a nuclear protein that interacts with the retinoid-related testis-associated receptor (RTR) and is able to inhibit the interaction of RTR with the N-CoR co-repressor. RAP80 has also been shown to interact with estrogen receptor alpha (ER-alpha) and modulate its activity. The modulation of ER-alpha activity is dependent on the ubiquitin-interacting motif (UIM) of RAP80. The UIM of RAP80 has also been demonstrated to be important for the BRCA1-dependent DNA repair response.

ID gène: 51720

NCBI Accession: NP_057374

UniProt: Q96RL1

Pathways: Réparation de l'ADN, Nuclear Hormone Receptor Binding, Positive Regulation of Response to DNA Damage Stimulus