PDE12 anticorps (AA 559-609)

N° du produit ABIN7449244

Détail du produit anti-PDE12 anticorps

Antigène: PDE12 (Phosphodiesterase 12 (PDE12))

Épitope: AA 559-609

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE12 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit anti-PDE12 Antibody, Affinity Purified

Homologie: Mouse,Rat,Bovine

Purification: Affinity Purified

Immunogène: Between AA 559 and 609

Isotype: IgG

Information d'application

Indications d'application: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PDE12

Antigène: PDE12 (Phosphodiesterase 12 (PDE12))

Autre désignation: PDE12 (PDE12 Produits)

Sujet: Background: PDE12 is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. It also cleaves 3',5'-phosphodiester bond of oligoadenylates and plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system [taken from the Universal Protein Resource (UniProt) Q6L8Q7].

ID gène: 201626

UniProt: Q6L8Q7