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Rad6 (N-Term) anticorps

Reactivité: Humain, Souris WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7449403
  • Antigène
    Rad6
    Épitope
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 5
    • 3
    • 2
    • 1
    Humain, Souris
    Hôte
    • 5
    Lapin
    Clonalité
    • 5
    Polyclonal
    Conjugué
    • 5
    Inconjugué
    Application
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Fonction
    Rabbit anti-Rad6 Antibody, Affinity Purified
    Homologie
    Rat,D. melanogaster,Bovine,Rabbit
    Purification
    Affinity Purified
    Immunogène
    N-terminus
    Isotype
    IgG
  • Indications d'application

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    WB: 1:10,000 - 1:25,000

    Restrictions
    For Research Use only
  • Concentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    12 months
  • Antigène
    Rad6
    Sujet
    Background: Rad 6, also known as Ubiquitin conjugating enzyme E2A, is an E2 enzyme of the three step ubiquitination pathway. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes, and the ligation of ubiquitin to the target protein by E3 enzymes. Ubiquitination provides an important post-translational means to regulate protein abundance and activity. Rad6 has been demonstrated to be important to DNA damage repair. Mutations in Rad6 cause an X-linked mental retardation syndrome.
    ID gène
    7319
    NCBI Accession
    NP_003327
    UniProt
    P49459
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