Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CD45RO anticorps

CD45RO Reactivité: Humain WB, IHC, IF (p), ICC, mIF Hôte: Souris Monoclonal UCHL-1 unconjugated
N° du produit ABIN7449553
  • Antigène Tous les produits CD45RO
    CD45RO
    Reactivité
    • 72
    • 12
    • 12
    • 11
    • 11
    Humain
    Hôte
    • 60
    • 12
    Souris
    Clonalité
    • 60
    • 12
    Monoclonal
    Conjugué
    • 11
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD45RO est non-conjugé
    Application
    • 56
    • 29
    • 25
    • 13
    • 12
    • 10
    • 10
    • 9
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Multiplex Immunofluorescence (mIF)
    Fonction
    Mouse anti-CD45RO Monoclonal Antibody, Purified [UCHL-1]
    Immunogène
    Cultured T-cells from an IL-2-dependent T-cell line (CA1)
    Clone
    UCHL-1
    Isotype
    IgG
  • Indications d'application

    IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 05:10:00

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    Phosphate Buffered Saline (PBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    12 months
  • Antigène
    CD45RO
    Autre désignation
    CD45RO (CD45RO Produits)
    Sujet
    Background: CD45RO is also known as protein tyrosine phosphatase receptor type C (PTPRC). It is a protein tyrosine phosphatase required for T-cell activation through the antigen receptor. CD45RO acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45RO recruits and dephosphorylates SKAP1 and FYN. It also dephosphorylates LYN, and thereby modulates LYN activity (By similarity)[taken from UniProtKB (Entry: P08575)].
    ID gène
    5788
    NCBI Accession
    NP_002829
    UniProt
    P08575
Vous êtes ici:
Support technique