Recombinant GZMB anticorps (AA 19-247)
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- Antigène Voir toutes GZMB Anticorps
- GZMB (Granzyme B (GZMB))
- Type d'anticorp
- Recombinant Antibody
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Épitope
- AA 19-247
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp GZMB est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Multiplex Immunofluorescence (mIF)
- Fonction
- Rabbit anti-Granzyme B Recombinant Monoclonal Antibody [BLR022E]
- Immunogène
- residues 19-247 (mature protein)
- Clone
- BLR022E
- Isotype
- IgG
- Top Product
- Discover our top product GZMB Anticorps primaire
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- Indications d'application
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IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 17:40:00
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 12 months
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- Antigène
- GZMB (Granzyme B (GZMB))
- Autre désignation
- Granzyme B (GZMB Produits)
- Synonymes
- anticorps CCPI, anticorps CGL-1, anticorps CGL1, anticorps CSP-B, anticorps CSPB, anticorps CTLA1, anticorps CTSGL1, anticorps HLP, anticorps SECT, anticorps granzyme B, anticorps GZMB
- Sujet
- Background: Granzyme B is a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing [taken from NCBI Entrez Gene (Gene ID: 3002)]
- ID gène
- 3002
- NCBI Accession
- NP_004122
- UniProt
- P10144
- Pathways
- Apoptose, Caspase Cascade in Apoptosis
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