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Recombinant CD8 alpha anticorps (AA 185-235)

CD8A Reactivité: Humain FACS, IHC, WB, IF (p), mIF Hôte: Lapin Monoclonal BLR044F unconjugated Recombinant Antibody

N° du produit ABIN7449561

Fiche de données

Antigène Voir toutes CD8 alpha (CD8A) Anticorps

CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Type d'anticorp

Recombinant Antibody
Épitope
16

15

10

9

9

9

8

7

6

6

5

5

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 185-235
Reactivité
205

117

47

45

15

7

3

2

2

1

1

1

1

1

1

1

1
Humain
Hôte
174

126

104
Lapin
Anticorps secondaires appropriés
Clonalité
297

103

1
Monoclonal
Conjugué
118

46

36

30

30

11

9

8

8

8

8

7

6

6

5

5

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp CD8 alpha est non-conjugé
Application
310

129

93

68

65

46

22

19

15

14

14

11

10

8

7

7

6

6

5

3

3

3

2

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Multiplex Immunofluorescence (mIF)

Fonction

Rabbit anti-CD8 alpha Recombinant Monoclonal Antibody [BLR044F]

Immunogène

between AA 185 and 235 (C-term)

Clone

BLR044F

Isotype

IgG

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CD8A Reactivité: Humain IHC, StM, ISt Hôte: Souris Monoclonal C8-468 unconjugated

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CD8A Reactivité: Souris, Rat FACS, IHC, WB, ELISA, ICC Hôte: Lapin Polyclonal unconjugated

Indications d'application

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
WB: 17:40:00

Restrictions

For Research Use only
Concentration

250 μg/mL

Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C

Date de péremption

12 months
Antigène

CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Autre désignation

CD8 alpha (CD8A Produits)

Synonymes

anticorps cd8, anticorps LOC100136450, anticorps BB154331, anticorps Ly-2, anticorps Ly-35, anticorps Ly-B, anticorps Lyt-2, anticorps zgc:136643, anticorps CD8, anticorps Leu2, anticorps MAL, anticorps p32, anticorps RHACD8-4, anticorps CD8a molecule, anticorps uncharacterized LOC100125537, anticorps CD8 alpha, anticorps CD8 antigen, alpha chain, anticorps T-cell surface glycoprotein CD8 alpha chain, anticorps Cd8a, anticorps LOC100125537, anticorps LOC100136450, anticorps CD8A, anticorps cd8a, anticorps LOC100126556

Sujet

Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain [taken from NCBI Entrez Gene (Gene ID: 925)].

ID gène

925

NCBI Accession

NP_001759

UniProt

P01732

Pathways

TCR Signaling