Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Claspin anticorps (AA 900-950)

CLSPN Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7449673
  • Antigène Voir toutes Claspin (CLSPN) Anticorps
    Claspin (CLSPN)
    Épitope
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 900-950
    Reactivité
    • 14
    • 1
    • 1
    Humain
    Hôte
    • 14
    Lapin
    Clonalité
    • 14
    Polyclonal
    Conjugué
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Claspin est non-conjugé
    Application
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Fonction
    Rabbit anti-Claspin Antibody, Affinity Purified
    Purification
    Affinity Purified
    Immunogène
    between AA 900 and 950
    Isotype
    IgG
    Top Product
    Discover our top product CLSPN Anticorps primaire
  • Indications d'application

    IP: 2 - 10 μg/mg lysate

    WB: 1:1,000 - 1:10,000

    Restrictions
    For Research Use only
  • Concentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    12 months
  • Antigène
    Claspin (CLSPN)
    Autre désignation
    Claspin (CLSPN Produits)
    Synonymes
    anticorps CLSPN, anticorps xClaspin, anticorps B130025E01, anticorps C85083, anticorps E130314M08Rik, anticorps claspin, anticorps claspin S homeolog, anticorps Clspn, anticorps CLSPN, anticorps clspn, anticorps clspn.S
    Sujet
    Background: Claspin is a checkpoint protein that interacts with and regulates checkpoint kinase 1 (Chk1) in response to replication stress. The interaction between claspin and Chk1 has been demonstrated to be required for ATR-dependent Chk1 activation. The interaction involves the phosphorylation of claspin that may be accomplished by Chk1 kinase activity. Claspin has been found to localize to chromatin in both the presence and absence of damaged DNA and to associate with PCNA, as an essential component of the DNA replication machinery. This association with the replication machinery may indicate a role for claspin in linking replication to DNA damage signaling and Chk1 activation.
    ID gène
    63967
    UniProt
    Q9HAW4
Vous êtes ici:
Support technique