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Stim2 anticorps (AA 650-700)

Stim2 Reactivité: Humain, Souris WB, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7449833
  • Antigène Voir toutes Stim2 Anticorps
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Épitope
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 650-700
    Reactivité
    • 37
    • 13
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 35
    • 1
    • 1
    Lapin
    Clonalité
    • 37
    Polyclonal
    Conjugué
    • 21
    • 5
    • 4
    • 3
    • 2
    • 2
    Cet anticorp Stim2 est non-conjugé
    Application
    • 33
    • 27
    • 19
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Fonction
    Rabbit anti-STIM2 Antibody, Affinity Purified
    Purification
    Affinity Purified
    Immunogène
    Between AA 650 and 700
    Isotype
    IgG
    Top Product
    Discover our top product Stim2 Anticorps primaire
  • Indications d'application

    IP: 2 - 10 μg/mg lysate

    WB: 1:1,000 - 1:5,000

    Restrictions
    For Research Use only
  • Concentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    12 months
  • Antigène
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Autre désignation
    STIM2 (Stim2 Produits)
    Synonymes
    anticorps STIM2, anticorps stromal interaction molecule 2, anticorps STIM2, anticorps stim2, anticorps Stim2
    Sujet
    Background: STIM2 (stromal interaction molecule 2) plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Stim2 functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. It regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, STIM2 translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI. STIM2 may inhibit STIM1-mediated Ca(2+) influx  [taken from the Universal Protein Resource (UniProt) Q9P246].
    ID gène
    57620
    NCBI Accession
    NP_065911
    UniProt
    Q9P246
    Pathways
    TCR Signaling, BCR Signaling
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