ERBB2IP anticorps (AA 825-875)

N° du produit ABIN7450219

Détail du produit anti-ERBB2IP anticorps

Antigène: ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))

Épitope: AA 825-875

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERBB2IP est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-Erbin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 825 and 875

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur ERBB2IP

Antigène: ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))

Autre désignation: Erbin (ERBB2IP Produits)

Synonymes: anticorps ERBIN, anticorps LAP2, anticorps ERBB2IP, anticorps 1700028E05Rik, anticorps Erbin, anticorps mKIAA1225, anticorps Erbb2i, anticorps Erbb2ip, anticorps RGD1562952, anticorps erbb2ip, anticorps zgc:152984, anticorps erbb2 interacting protein, anticorps apurinic/apyrimidinic endodeoxyribonuclease 1, anticorps Erbb2 interacting protein, anticorps ERBIN, anticorps ERBB2IP, anticorps erbin, anticorps Erbin

Sujet: Background: Erbin (Erbb2-interacting protein) is a member of the leucine-rich repeat and PDZ domain (LAP) family. Erbin contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction [taken from NCBI Entrez Gene (Gene ID: 55914)].

ID gène: 55914

UniProt: Q96RT1

Pathways: EGFR Signaling Pathway, Asymmetric Protein Localization