NBR1 anticorps (AA 916-966)

N° du produit ABIN7450479

Détail du produit anti-NBR1 anticorps

Antigène: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Épitope: AA 916-966

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NBR1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-NBR1 Antibody, Affinity Purified

Homologie: Orangutan

Purification: Affinity Purified

Immunogène: Between AA 916 and 966

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NBR1

Antigène: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Autre désignation: NBR1 (NBR1 Produits)

Synonymes: anticorps fa99f08, anticorps wu:fa99f08, anticorps MGC69008, anticorps NBR1, anticorps 1A1-3B, anticorps M17S2, anticorps mKIAA0049, anticorps Ca125, anticorps RGD1311421, anticorps neighbor of brca1 gene 1a, anticorps neighbor of BRCA1 gene 1 L homeolog, anticorps NBR1, autophagy cargo receptor, anticorps neighbor of Brca1 gene 1, anticorps nbr1a, anticorps nbr1.L, anticorps NBR1, anticorps Nbr1

Sujet: Background: NBR1 (Next to BRCA1 gene 1 protein) was originally identified as an ovarian tumor antigen monitored in ovarian cancer.NBR1 contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. The gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene [taken from NCBI Entrez Gene (Gene ID: 4077)].

ID gène: 4077

UniProt: Q14596

Pathways: Autophagy