SH3BP2 anticorps (AA 150-200)

N° du produit ABIN7450726

Détail du produit anti-SH3BP2 anticorps

Antigène: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Épitope: AA 150-200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3BP2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-SH3BP2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 150 and 200

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SH3BP2

Antigène: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Autre désignation: SH3BP2 (SH3BP2 Produits)

Synonymes: anticorps SH3BP2, anticorps 3BP-2, anticorps 3BP2, anticorps CRBM, anticorps CRPM, anticorps SH3 domain binding protein 2, anticorps SH3-domain binding protein 2, anticorps SH3BP2, anticorps Sh3bp2

Sujet: Background: SH3 domain-binding protein 2 (SH3BP2) N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism, an autosomal dominant inherited syndrome characterized by excessive bone degradation of the upper and lower jaws followed by development of fibrous tissue masses and characteristic facial swelling [taken from NCBI Entrez Gene (Gene ID: 6452)].

ID gène: 6452

NCBI Accession: NP_001116153

UniProt: P78314

Pathways: TCR Signaling