SBDS anticorps (AA 175-225)

N° du produit ABIN7450730

Détail du produit anti-SBDS anticorps

Antigène: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Épitope: AA 175-225

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SBDS est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-Shwachman-Bodian-Diamond Syndrome/SBDS Antibody, Affinity Purified

Homologie: Bovine,Orangutan

Purification: Affinity Purified

Immunogène: Between AA 175 and 225

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SBDS

Antigène: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Autre désignation: Shwachman-Bodian-Diamond Syndrome/SBDS (SBDS Produits)

Synonymes: anticorps cgi-97, anticorps sds, anticorps swds, anticorps zgc:56700, anticorps SDS, anticorps SWDS, anticorps 4733401P19Rik, anticorps AI836084, anticorps CGI-97, anticorps SBDS ribosome assembly guanine nucleotide exchange factor, anticorps hypothetical protein, anticorps SBDS, ribosome maturation factor, anticorps SBDS ribosome assembly guanine nucleotide exchange factor S homeolog, anticorps SBDS ribosome maturation factor, anticorps sbds, anticorps LOAG_04440, anticorps sbds.S, anticorps SBDS, anticorps Sbds

Sujet: Background: Shwachman-Bodian-Diamond Syndrome/SBDS is required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, it triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. SBDS is required for normal levels of protein synthesis. It may play a role in cellular stress resistance and cellular response to DNA damage. It may also play a role in cell proliferation [taken from the Universal Protein Resource (UniProt) Q9Y3A5].

ID gène: 51119

UniProt: Q9Y3A5

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly