SPG20 anticorps (AA 350-400)

N° du produit ABIN7450761

Détail du produit anti-SPG20 anticorps

Antigène: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Épitope: AA 350-400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPG20 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-SPG20 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 350 and 400

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SPG20

Antigène: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Autre désignation: SPG20 (SPG20 Produits)

Synonymes: anticorps SPARTIN, anticorps TAHCCP1, anticorps AI840044, anticorps C79168, anticorps mKIAA0610, anticorps spartin, anticorps Spg20, anticorps spg20a, anticorps zgc:172059, anticorps spg20b, anticorps zgc:153766, anticorps spartin, anticorps spastic paraplegia 20, spartin (Troyer syndrome) homolog (human), anticorps spartin a, anticorps spartin b, anticorps SPART, anticorps Spg20, anticorps Spart, anticorps sparta, anticorps spartb

Sujet: Background: Spastic paraplegia 20 protein (SPG20) is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Mutations associated with the SPG20 gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome) [taken from NCBI Entrez Gene (Gene ID: 23111)].

ID gène: 23111

UniProt: Q8N0X7

Pathways: Regulation of Cell Size, SARS-CoV-2 Protein Interactome