Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 2340-2390) anticorps

N° du produit ABIN7450766

Détail du produit

Antigène: Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

Épitope: AA 2340-2390

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-SPTBN2/SCA5 Antibody, Affinity Purified

Homologie: Rat

Purification: Affinity Purified

Immunogène: between AA 2340 and 2390

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détail du antigène

Antigène: Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

Autre désignation: SPTBN2/SCA5 (SPTBN2 Produits)

Synonymes: anticorps Spnb3, anticorps mKIAA0302, anticorps GTRAP41, anticorps SCA5, anticorps spectrin beta, non-erythrocytic 2, anticorps spectrin, beta, non-erythrocytic 2, anticorps Sptbn2, anticorps SPTBN2

Sujet: Background: SPTBN2/SCA5 is a member of the beta spectrin gene family and a subunit of the spectrin cytoskeletal scaffolding protein that links the plasma membrane to cytoskeletal actin and functions in cellular shape and organelle organization. SPTBN2/SCA5 has been identified as a Golgi- and vesicle-associated spectrin. Mutations in SPTBN2/SCA5 cause spinocerebellar ataxia type 5 (SCA5), an autosomal dominant disease characterized by progressive incoordination of gait, hand, speech, and eye movements.

ID gène: 6712

NCBI Accession: NP_008877

UniProt: O15020

Pathways: Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis