VTA1 anticorps (AA 250-300)

N° du produit ABIN7450903

Détail du produit anti-VTA1 anticorps

Antigène: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Épitope: AA 250-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VTA1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-VTA1/LIP5 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 250 and 300

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur VTA1

Antigène: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Autre désignation: VTA1/LIP5 (VTA1 Produits)

Synonymes: anticorps C6orf55, anticorps DRG-1, anticorps DRG1, anticorps LIP5, anticorps My012, anticorps SBP1, anticorps 1110001D18Rik, anticorps 1110059P08Rik, anticorps AU040813, anticorps C85340, anticorps Lip5, anticorps RGD1305031, anticorps Vps20-associated 1 homolog, anticorps vesicle trafficking 1, anticorps vesicle (multivesicular body) trafficking 1, anticorps Vta1, anticorps VTA1

Sujet: Background: VTA1 is involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. VTA1 is thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. It is involved in the sorting and down-regulation of EGFR (By similarity) [taken from the Universal Protein Resource (UniProt) Q9NP79].

ID gène: 51534

UniProt: Q9NP79