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SPEN anticorps (AA 1350-1400)

SPEN Reactivité: Humain IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7451040
  • Antigène Voir toutes SPEN Anticorps
    SPEN (Spen Homolog, Transcriptional Regulator (SPEN))
    Épitope
    • 2
    • 1
    • 1
    AA 1350-1400
    Reactivité
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 4
    • 1
    Lapin
    Clonalité
    • 5
    Polyclonal
    Conjugué
    • 5
    Cet anticorp SPEN est non-conjugé
    Application
    • 3
    • 2
    Immunoprecipitation (IP)
    Fonction
    Rabbit anti-SHARP Antibody, Affinity Purified
    Homologie
    Mouse
    Purification
    Affinity Purified
    Immunogène
    between AA 1350 and 1400
    Isotype
    IgG
    Top Product
    Discover our top product SPEN Anticorps primaire
  • Indications d'application

    IP: 2 - 10 μg/mg lysate

    WB: Not recommended for crude preparations. ABIN7451040 can be used successfully for WB of enriched preparations (e.g. immunoprecipitated) SHARP.

    Restrictions
    For Research Use only
  • Concentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    12 months
  • Antigène
    SPEN (Spen Homolog, Transcriptional Regulator (SPEN))
    Autre désignation
    SHARP (SPEN Produits)
    Synonymes
    anticorps HIAA0929, anticorps MINT, anticorps RBM15C, anticorps SHARP, anticorps Mint, anticorps mKIAA0929, anticorps spen family transcriptional repressor, anticorps SPEN homolog, transcriptional regulator (Drosophila), anticorps SPEN, anticorps Spen
    Sujet
    Background: SHARP functions as a transcriptional repressor by interacting with proteins involved in deacetylation such as the NuRD (nucleosome remodeling) complex. SHARP can also repress transcription by interacting with corepressors such as SMRT/NCoR (silencing mediator for retinoid and thyroid receptors/nuclear receptor corepressor). SHARP is able to suppress transcription through the Notch/RBP-J signaling pathway by competing RBP-J binding with the intracellular domain of Notch.
    ID gène
    23013
    NCBI Accession
    NP_055816
    UniProt
    Q96T58
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