NSMCE2 anticorps (AA 197-247)

N° du produit ABIN7451060

Détail du produit anti-NSMCE2 anticorps

Antigène: NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Épitope: AA 197-247

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NSMCE2 est non-conjugé

Application: Immunoprecipitation (IP)

Fonction: Rabbit anti-MMS21 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 197 and 247

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451060 has not performed satisfactorily when used for WB of MMS21 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MMS21.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NSMCE2

Antigène: NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Autre désignation: MMS21 (NSMCE2 Produits)

Synonymes: anticorps 1110014D18Rik, anticorps AI661537, anticorps RGD1305156, anticorps C8orf36, anticorps MMS21, anticorps NSE2, anticorps ZMIZ7, anticorps Non-SMC element 2, anticorps NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase, anticorps NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog, anticorps Smc5-6 complex non-SMC subunit 2, anticorps Nsmce2, anticorps NSMCE2, anticorps nsmce2.L, anticorps nse2

Sujet: Background: The human MMS21 (Methyl Methanesulfonate-Sensitivity protein 21) homolog is also known as E3 SUMO-protein ligase NSE2. MMS21 is an E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand break repair by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks [taken from the Universal Protein Resource (UniProt) Q96MF7].

ID gène: 286053

NCBI Accession: NP_775956

UniProt: Q96MF7