LZTS2 anticorps (C-Term)

N° du produit ABIN7451099

Détail du produit anti-LZTS2 anticorps

Antigène: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LZTS2 est non-conjugé

Application: Immunoprecipitation (IP)

Fonction: Rabbit anti-LZTS2 Antibody, Affinity Purified

Homologie: Mouse,Rat,Bovine

Purification: Affinity Purified

Immunogène: Between AA 660 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451099 has not performed satisfactorily when used for WB of LZTS2 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of LZTS2.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur LZTS2

Antigène: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Autre désignation: LZTS2 (LZTS2 Produits)

Synonymes: anticorps lapser1, anticorps MGC89253, anticorps si:dkey-250a11.1, anticorps LAPSER1, anticorps BC014695, anticorps mKIAA1813, anticorps Lapser1, anticorps leucine zipper, putative tumor suppressor 2, anticorps leucine zipper tumor suppressor 2, anticorps leucine zipper, putative tumor suppressor 2a, anticorps leucine zipper, putative tumor suppressor 2 S homeolog, anticorps lzts2, anticorps LZTS2, anticorps lzts2a, anticorps Lzts2, anticorps lzts2.S

Sujet: Background: leucine zipper, putative tumor suppressor 2 (LZTS2) is az negative regulator of katanin-mediated microtubule severing and release from the centrosome. It is required for central spindle formation and the completion of cytokinesis. LZTS2 may negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. It is a negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin  [taken from the Universal Protein Resource (UniProt) Q9BRK4].

ID gène: 84445

UniProt: Q9BRK4