RFWD2 anticorps (AA 100-150)
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- Antigène Voir toutes RFWD2 Anticorps
- RFWD2 (Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2))
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Épitope
- AA 100-150
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RFWD2 est non-conjugé
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Application
- Immunoprecipitation (IP)
- Fonction
- Rabbit anti-COP1/RFWD2 Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogène
- between AA 100 and 150
- Isotype
- IgG
- Top Product
- Discover our top product RFWD2 Anticorps primaire
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- Indications d'application
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-COP1/RFWD2 antibody ABIN7450133.
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 12 months
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- Antigène
- RFWD2 (Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2))
- Autre désignation
- COP1/RFWD2 (RFWD2 Produits)
- Synonymes
- anticorps COP1, anticorps RNF200, anticorps AI316802, anticorps C80879, anticorps Cop1, anticorps RGD1304773, anticorps RFWD2, anticorps cop1, anticorps rnf200, anticorps zgc:163067, anticorps ring finger and WD repeat domain 2, anticorps ring finger and WD repeat domain 2, E3 ubiquitin protein ligase, anticorps ring finger and WD repeat domain 2, E3 ubiquitin protein ligase L homeolog, anticorps RFWD2, anticorps Rfwd2, anticorps rfwd2, anticorps rfwd2.L
- Sujet
- Background: Constitutive photomorphogenic protein 1 (COP1) has been characterized in plants as a RING-finger-containing protein that functions to repress plant photomorphogenesis. In mammals, COP1 has been identified as an E3 ubiquitin ligase that negatively regulates p53 protein levels in unstressed cells. In response to DNA damage COP1 is phosphorylated by the ataxia telangiectasia mutated (ATM) protein kinase and is rapidly degraded releasing p53 to exert its tumor suppressor activities.
- ID gène
- 64326
- NCBI Accession
- NP_071902
- UniProt
- Q8NHY2
- Pathways
- Photoperiodism
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