Importin 11 anticorps (AA 825-875)
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- Antigène Voir toutes Importin 11 (IPO11) Anticorps
- Importin 11 (IPO11)
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Épitope
- AA 825-875
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Importin 11 est non-conjugé
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Application
- Immunoprecipitation (IP)
- Fonction
- Rabbit anti-Importin 11/IPO11 Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogène
- Between AA 825 and 875
- Isotype
- IgG
- Top Product
- Discover our top product IPO11 Anticorps primaire
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- Indications d'application
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-Importin 11/IPO11 antibody ABIN7450360.
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 12 months
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- Antigène
- Importin 11 (IPO11)
- Autre désignation
- Importin 11/IPO11 (IPO11 Produits)
- Synonymes
- anticorps MGC83107, anticorps IPO11, anticorps slrn, anticorps ranbp11, anticorps RanBP11, anticorps 1700081H05Rik, anticorps 2510001A17Rik, anticorps AI314624, anticorps AW555235, anticorps E330021B14Rik, anticorps Ranbp11, anticorps importin 11 S homeolog, anticorps importin 11, anticorps importin-11, anticorps ipo11.S, anticorps ipo11, anticorps IPO11, anticorps AFUA_1G03590, anticorps BDBG_04626, anticorps LOC100162908, anticorps Ipo11
- Sujet
- Background: Importin 11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates, and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Importin 11/IPO11 mediates the nuclear import of UBE2E3, and of RPL12 (By similarity) [taken from the Universal Protein Resource (UniProt) Q9UI26].
- ID gène
- 51194
- UniProt
- Q9UI26
- Pathways
- Protein targeting to Nucleus
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