IGKV1-27 anticorps (AA 525-575)

N° du produit ABIN7451604

Détail du produit anti-IGKV1-27 anticorps

Antigène: IGKV1-27 (Immunoglobulin kappa Variable 1-27 (IGKV1-27))

Épitope: AA 525-575

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGKV1-27 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-A20 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 525 and 575

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur IGKV1-27

Antigène: IGKV1-27 (Immunoglobulin kappa Variable 1-27 (IGKV1-27))

Autre désignation: A20 (IGKV1-27 Produits)

Synonymes: anticorps A20, anticorps OTUD7C, anticorps TNFA1P2, anticorps TNF alpha induced protein 3, anticorps TNFAIP3

Sujet: Background: Zinc-finger protein A20 was identified as a transcript that was rapidly induced by tumor-necrosis factor alpha (TNF-alpha). A20 is an essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Upon TNF stimulation, A20 deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains [taken from the Universal Protein Resource (UniProt) P21580].

ID gène: 7128

NCBI Accession: NP_006281

UniProt: P21580

Pathways: Activation of Innate immune Response