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AKAP8L anticorps (AA 525-575)

AKAP8L Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7451617
  • Antigène Voir toutes AKAP8L Anticorps
    AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))
    Épitope
    • 10
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 525-575
    Reactivité
    • 37
    • 13
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 37
    Lapin
    Clonalité
    • 37
    Polyclonal
    Conjugué
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AKAP8L est non-conjugé
    Application
    • 27
    • 18
    • 8
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Fonction
    Rabbit anti-AKAP8L/HA95 Antibody, Affinity Purified
    Purification
    Affinity Purified
    Immunogène
    between AA 525 and 575
    Isotype
    IgG
    Top Product
    Discover our top product AKAP8L Anticorps primaire
  • Indications d'application

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    12 months
  • Antigène
    AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))
    Autre désignation
    AKAP8L/HA95 (AKAP8L Produits)
    Synonymes
    anticorps HA95, anticorps HAP95, anticorps NAKAP, anticorps NAKAP95, anticorps Nakap95, anticorps zgc:85966, anticorps AKAP8L, anticorps A-kinase anchoring protein 8 like, anticorps A kinase (PRKA) anchor protein 8-like, anticorps A-kinase anchoring protein 8 like L homeolog, anticorps AKAP8L, anticorps Akap8l, anticorps akap8l, anticorps akap8l.L
    Sujet
    Background: AKAP8L/HA95 is a PKA anchoring protein that is localized to the nuclear envelope and associates with chromatin upon nuclear envelope breakdown during mitosis. AKAP8L/HA95 has been found to play an important role in the initiation of DNA replication and may function as a scaffold for proteins such as MCM2 and LAP2beta. Additionally, AKAP8L/HA95 has been shown to co-locate with the PKA C subunit in splicing factor compartments and is involved in the regulation of pre-mRNA splicing. Further support for a scaffolding and splicing role in the nucleus comes from the observation that AKAP8L/HA95 colocalizes with HypA, a splicing-like factor, and through this association may function as a docking site for the nuclear accumulation of Huntington protein as seen in Huntington's disease.
    ID gène
    26993
    NCBI Accession
    NP_055186
    UniProt
    Q9ULX6
    Pathways
    SARS-CoV-2 Protein Interactome
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