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SPAG5 anticorps (AA 875-925)

SPAG5 Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7451646
  • Antigène Voir toutes SPAG5 Anticorps
    SPAG5 (Sperm Associated Antigen 5 (SPAG5))
    Épitope
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 875-925
    Reactivité
    • 17
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 17
    • 1
    Lapin
    Clonalité
    • 17
    • 1
    Polyclonal
    Conjugué
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SPAG5 est non-conjugé
    Application
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Fonction
    Rabbit anti-Astrin/MAP126 Antibody, Affinity Purified
    Purification
    Affinity Purified
    Immunogène
    between AA 875 and 925
    Isotype
    IgG
    Top Product
    Discover our top product SPAG5 Anticorps primaire
  • Indications d'application

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    12 months
  • Antigène
    SPAG5 (Sperm Associated Antigen 5 (SPAG5))
    Autre désignation
    Astrin/MAP126 (SPAG5 Produits)
    Synonymes
    anticorps SPAG5, anticorps DEEPEST, anticorps MAP126, anticorps hMAP126, anticorps AI874642, anticorps D11Bhm180e, anticorps Deepest, anticorps Mastrin, anticorps S17, anticorps sperm associated antigen 5, anticorps sperm-associated antigen 5, anticorps SPAG5, anticorps LOC739263, anticorps Spag5
    Sujet
    Background: Astrin/MAP126 has been identified as a mitotic spindle-associated protein essential for centrosome integrity and the progression through mitosis. Astrin/MAP126 interacts with Ninein and Aurora-A at the centrosome. Ninein, but not Aurora-A, appears to be required for proper localization of Astrin/MAP126 to the centrosome during S and G2 phase. A pool of Astrin/MAP126 also localizes to the outer kinetochore where it plays an essential role in chromatid adhesion and chromosome congression and segregation. The localization of Astrin/MAP126 to the spindle pole and kinetochore has been shown to be dependent on its phosphorylation by glycogen synthase kinase 3beta (GSK3beta).
    ID gène
    10615
    NCBI Accession
    NP_006452
    UniProt
    Q96R06
    Pathways
    M Phase
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