ASXL2 anticorps (AA 600-650)

N° du produit ABIN7451647

Détail du produit anti-ASXL2 anticorps

Antigène: ASXL2 (Additional Sex Combs Like 2 (ASXL2))

Épitope: AA 600-650

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASXL2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-ASXL2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 600 and 650

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur ASXL2

Antigène: ASXL2 (Additional Sex Combs Like 2 (ASXL2))

Autre désignation: ASXL2 (ASXL2 Produits)

Synonymes: anticorps asxh2, anticorps ASXH2, anticorps 4930556B16Rik, anticorps mKIAA1685, anticorps additional sex combs like 2, transcriptional regulator, anticorps additional sex combs like 2 (Drosophila), anticorps Asxl2, anticorps ASXL2, anticorps asxl2

Sujet: Background: The gene that encodes Additional sex combs-like protein 2 (ASXL2) is a homolog of the drosophila additional sex combs (Asx) gene. Drosophila Asx is in a class of proteins known as ETP (enhancers of trithorax and polycomb). ETP proteins regulate polycomb-group (PcG) and trithorax-group (trxG) proteins which function to modify the methylation of histones and structure of chromatin. Mutations in ASXL1 are implicated in the development of myelodysplastic syndromes (MDS), a group of hematological diseases characterized by ineffective hematopoiesis and a predisposition to acute myeloid leukemia (AML).

ID gène: 55252

NCBI Accession: NP_060733

UniProt: Q76L83

Pathways: Positive Regulation of fat Cell Differentiation