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CIZ1 anticorps (AA 848-898)

CIZ1 Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7451705
  • Antigène Voir toutes CIZ1 Anticorps
    CIZ1 (CDKN1A Interacting Zinc Finger Protein 1 (CIZ1))
    Épitope
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 848-898
    Reactivité
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 15
    • 1
    • 1
    Lapin
    Clonalité
    • 17
    Polyclonal
    Conjugué
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CIZ1 est non-conjugé
    Application
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Fonction
    Rabbit anti-CIZ1 Antibody, Affinity Purified
    Purification
    Affinity Purified
    Immunogène
    between AA 848 and 898
    Isotype
    IgG
    Top Product
    Discover our top product CIZ1 Anticorps primaire
  • Indications d'application

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions
    For Research Use only
  • Concentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    12 months
  • Antigène
    CIZ1 (CDKN1A Interacting Zinc Finger Protein 1 (CIZ1))
    Autre désignation
    CIZ1 (CIZ1 Produits)
    Synonymes
    anticorps LSFR1, anticorps NP94, anticorps ZNF356, anticorps CIZ1, anticorps 0610038H21Rik, anticorps 2900056O04Rik, anticorps ciz1, anticorps wu:fi12g11, anticorps wu:fi27d02, anticorps zgc:66467, anticorps CDKN1A interacting zinc finger protein 1, anticorps cip1-interacting zinc finger protein, anticorps cdkn1a interacting zinc finger protein 1b, anticorps CIZ1, anticorps LOC464765, anticorps Ciz1, anticorps ciz1b
    Sujet
    Background: CIZ1 (Cip1 interacting zinc-finger protein) was identified as a protein that associates with the cell-cycle inhibiting protein, p21 (Cip1/Waf1). CIZ1 is a member of the matrin 3 protein family and has been shown to bind DNA consensus sequences and co-localize with PCNA during replication. In breast cancer cells, CIZ1 was shown to associate with Cdk2 and dynein light chain 1 (DLC1), a cytoskeletal signaling protein involved in cell cycle regulation and tumorigenesis. Studies of the role of CIZ1 in breast tumorigenesis revealed that CIZ1 is an estrogen-responsive gene that functions as a coactivator of the estrogen receptor. Targeted depletion of CIZ1 inhibits entry into S-phase. This finding along with evidence that CIZ1 interacts with multiple cell cycle regulatory proteins and localizes to DNA replication foci, indicates that CIZ1 plays a critical role in the regulation of DNA replication.
    ID gène
    25792
    NCBI Accession
    NP_036259
    UniProt
    Q9ULV3
    Pathways
    Maintenance of Protein Location
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