GEMIN5 anticorps (AA 1360-1410)

N° du produit ABIN7451794

Détail du produit anti-GEMIN5 anticorps

Antigène: GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))

Épitope: AA 1360-1410

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GEMIN5 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-Gemin5 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1360 and 1410

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur GEMIN5

Antigène: GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))

Autre désignation: Gemin5 (GEMIN5 Produits)

Synonymes: anticorps GEMIN-5, anticorps AA407055, anticorps AA407208, anticorps AI451603, anticorps BB194447, anticorps C330013N08, anticorps gem nuclear organelle associated protein 5, anticorps gem (nuclear organelle) associated protein 5, anticorps GEMIN5, anticorps Gemin5

Sujet: Background: Gemin5 is a component of the SMN (survival of motor neurons) complex. The SMN complex is composed of the SMN protein and several Gemins (2-7) and is involved in the assembly of snRNPs in the cytoplasm and their transport to the nucleus. The SMN complex localizes to nuclear focal structures called gems or Gemini of coiled bodies. Gemin 5 has been shown to be responsible for recognizing and binding the snRNP code during snRNP biogenesis. Recent studies have shown that Gemin 5 is rarely detectable in SMN complexes associated with gems/Cajal bodies in the nucleus and may play a specific role in cytoplasmic SMN complexes. It has also been shown to function as a scaffold protein for ASK1-JNK1 signaling.

ID gène: 25929

NCBI Accession: NP_056280

UniProt: Q8TEQ6

Pathways: Ribonucleoprotein Complex Subunit Organization