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GEMIN5 anticorps (AA 1410-1438)

GEMIN5 Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7451795
  • Antigène Voir toutes GEMIN5 Anticorps
    GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
    Épitope
    • 1
    • 1
    • 1
    AA 1410-1438
    Reactivité
    • 5
    • 1
    Humain
    Hôte
    • 5
    Lapin
    Clonalité
    • 5
    Polyclonal
    Conjugué
    • 5
    Cet anticorp GEMIN5 est non-conjugé
    Application
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Fonction
    Rabbit anti-Gemin5 Antibody, Affinity Purified
    Purification
    Affinity Purified
    Immunogène
    between AA 1410 and 1438
    Isotype
    IgG
    Top Product
    Discover our top product GEMIN5 Anticorps primaire
  • Indications d'application

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    12 months
  • Antigène
    GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
    Autre désignation
    Gemin5 (GEMIN5 Produits)
    Synonymes
    anticorps GEMIN-5, anticorps AA407055, anticorps AA407208, anticorps AI451603, anticorps BB194447, anticorps C330013N08, anticorps gem nuclear organelle associated protein 5, anticorps gem (nuclear organelle) associated protein 5, anticorps GEMIN5, anticorps Gemin5
    Sujet
    Background: Gemin5 is a component of the SMN (survival of motor neurons) complex. The SMN complex is composed of the SMN protein and several Gemins (2-7) and is involved in the assembly of snRNPs in the cytoplasm and their transport to the nucleus. The SMN complex localizes to nuclear focal structures called gems or Gemini of coiled bodies. Gemin 5 has been shown to be responsible for recognizing and binding the snRNP code during snRNP biogenesis. Recent studies have shown that Gemin 5 is rarely detectable in SMN complexes associated with gems/Cajal bodies in the nucleus and may play a specific role in cytoplasmic SMN complexes. It has also been shown to function as a scaffold protein for ASK1-JNK1 signaling.
    ID gène
    25929
    NCBI Accession
    NP_056280
    UniProt
    Q8TEQ6
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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