GEMIN5 anticorps (AA 1410-1438)
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- Antigène Voir toutes GEMIN5 Anticorps
- GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
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Épitope
- AA 1410-1438
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GEMIN5 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Fonction
- Rabbit anti-Gemin5 Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogène
- between AA 1410 and 1438
- Isotype
- IgG
- Top Product
- Discover our top product GEMIN5 Anticorps primaire
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- Indications d'application
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 12 months
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- Antigène
- GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
- Autre désignation
- Gemin5 (GEMIN5 Produits)
- Synonymes
- anticorps GEMIN-5, anticorps AA407055, anticorps AA407208, anticorps AI451603, anticorps BB194447, anticorps C330013N08, anticorps gem nuclear organelle associated protein 5, anticorps gem (nuclear organelle) associated protein 5, anticorps GEMIN5, anticorps Gemin5
- Sujet
- Background: Gemin5 is a component of the SMN (survival of motor neurons) complex. The SMN complex is composed of the SMN protein and several Gemins (2-7) and is involved in the assembly of snRNPs in the cytoplasm and their transport to the nucleus. The SMN complex localizes to nuclear focal structures called gems or Gemini of coiled bodies. Gemin 5 has been shown to be responsible for recognizing and binding the snRNP code during snRNP biogenesis. Recent studies have shown that Gemin 5 is rarely detectable in SMN complexes associated with gems/Cajal bodies in the nucleus and may play a specific role in cytoplasmic SMN complexes. It has also been shown to function as a scaffold protein for ASK1-JNK1 signaling.
- ID gène
- 25929
- NCBI Accession
- NP_056280
- UniProt
- Q8TEQ6
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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