PALB2 anticorps (AA 200-250)

N° du produit ABIN7451934

Détail du produit anti-PALB2 anticorps

Antigène: PALB2 (Partner and Localizer of BRCA2 (PALB2))

Épitope: AA 200-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PALB2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-PALB2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 200 and 250

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PALB2

Antigène: PALB2 (Partner and Localizer of BRCA2 (PALB2))

Autre désignation: PALB2 (PALB2 Produits)

Sujet: Background: PALB2 (partner and localizer of BRCA2) interacts with BRCA2 and promotes BRCA2 localization and stability. PALB2 is also known as FANCN. Bi-allelic mutations in PALB2 result in Fanconi anemia disorder and breast cancer susceptibility. At the cellular level, PALB2 is important to the DNA damage response and chromosome stability and is essential to BRCA2 function.

ID gène: 79728

NCBI Accession: NP_078951

UniProt: Q86YC2

Pathways: Réparation de l'ADN