SOS1 anticorps (AA 1283-1333)

N° du produit ABIN7452055

Détail du produit anti-SOS1 anticorps

Antigène: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Épitope: AA 1283-1333

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOS1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-SOS1 Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 1283 and 1333

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SOS1

Antigène: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Autre désignation: SOS1 (SOS1 Produits)

Synonymes: anticorps GF1, anticorps GGF1, anticorps GINGF, anticorps HGF, anticorps NS4, anticorps 4430401P03Rik, anticorps 9630010N06, anticorps AI449023, anticorps SOS Ras/Rac guanine nucleotide exchange factor 1, anticorps son of sevenless homolog 1 (Drosophila), anticorps SOS1, anticorps Sos1

Sujet: Background: SOS1 (son of sevenless homolog 1) is a human paralog of the drosophila SOS gene. Drosophila SOS was originally identified as a gene that functioned downstream of the sevenless gene in the Ras/MAP kinase signaling pathway. SOS and its paralogs, SOS1 and SOS2, function as guanine nucleotide exchange factors that act on Ras-GTPases to cause release of GDP in exchange for GTP. Mutations in SOS1 are the cause of Noonan syndrome type 4 and gingival fibromatosis.

ID gène: 6654

NCBI Accession: NP_005624

UniProt: Q07889

Pathways: Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling