USP20 anticorps (AA 863-913)
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- Antigène Voir toutes USP20 Anticorps
- USP20 (Ubiquitin Specific Peptidase 20 (USP20))
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Épitope
- AA 863-913
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp USP20 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Fonction
- Rabbit anti-USP20/VDU2 Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogène
- between AA 863 and 913
- Isotype
- IgG
- Top Product
- Discover our top product USP20 Anticorps primaire
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- Indications d'application
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 12 months
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- Antigène
- USP20 (Ubiquitin Specific Peptidase 20 (USP20))
- Autre désignation
- USP20/VDU2 (USP20 Produits)
- Synonymes
- anticorps USP20, anticorps vdu2, anticorps lsfr3a, anticorps LSFR3A, anticorps VDU2, anticorps hVDU2, anticorps 1700055M05Rik, anticorps AI467231, anticorps Vdu2, anticorps im:7151955, anticorps zgc:63661, anticorps universal stress protein, anticorps ubiquitin specific peptidase 20, anticorps ubiquitin specific peptidase 20 L homeolog, anticorps RR_RS15875, anticorps USP20, anticorps usp20, anticorps Usp20, anticorps usp20.L
- Sujet
- Background: The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific peptidase 20 (USP20) is a UBP and is also called von-Hippel-Lindau protein (pVHL) interacting deubiquitinating enzyme 2 (VDU2). pVHL is an E3 ubiquitin-ligase that ubiquitinates hypoxia-inducible factor (HIF)-1alpha. USP20/VDU2 functions to specifically deubiquitinate HIF-1alpha to increase expression of HIF-1alpha regulated genes.
- ID gène
- 10868
- NCBI Accession
- NP_006667
- UniProt
- Q9Y2K6
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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