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BRAP anticorps (AA 510-560)

BRAP Reactivité: Humain IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7452274
  • Antigène Voir toutes BRAP Anticorps
    BRAP (BRCA1 Associated Protein (BRAP))
    Épitope
    • 14
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 510-560
    Reactivité
    • 29
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 28
    • 1
    Lapin
    Clonalité
    • 28
    • 1
    Polyclonal
    Conjugué
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp BRAP est non-conjugé
    Application
    • 23
    • 20
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunoprecipitation (IP)
    Fonction
    Rabbit anti-BRAP Antibody, Affinity Purified
    Purification
    Affinity Purified
    Immunogène
    between AA 510 and 560
    Isotype
    IgG
    Top Product
    Discover our top product BRAP Anticorps primaire
  • Indications d'application

    IP: 2 - 5 μg/mg lysate

    WB: Not recommended. Use rabbit anti-BRAP antibody ABIN7451664.

    Restrictions
    For Research Use only
  • Concentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    12 months
  • Antigène
    BRAP (BRCA1 Associated Protein (BRAP))
    Autre désignation
    BRAP (BRAP Produits)
    Synonymes
    anticorps imp, anticorps MGC68778, anticorps zgc:92894, anticorps BRAP, anticorps BRAP2, anticorps IMP, anticorps RNF52, anticorps 3010002G07Rik, anticorps BRCA1 associated protein S homeolog, anticorps BRCA1 associated protein, anticorps BRCA1-associated protein, anticorps brca1-associated protein, anticorps brap.S, anticorps brap, anticorps BRAP, anticorps NAEGRDRAFT_81654, anticorps CC1G_00971, anticorps CpipJ_CPIJ003557, anticorps Tsp_05101, anticorps LOC100282389, anticorps Brap
    Sujet
    Background: BRCA1-associated protein (BRAP) negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. BRAP acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. BRAP may also act as a cytoplasmic retention protein with a role in regulating nuclear transport [taken from the Universal Protein Resource (UniProt) Q7Z569].
    ID gène
    8315
    NCBI Accession
    NP_006759
    UniProt
    Q7Z569
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