BRAP anticorps (AA 510-560)
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- Antigène Voir toutes BRAP Anticorps
- BRAP (BRCA1 Associated Protein (BRAP))
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Épitope
- AA 510-560
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BRAP est non-conjugé
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Application
- Immunoprecipitation (IP)
- Fonction
- Rabbit anti-BRAP Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogène
- between AA 510 and 560
- Isotype
- IgG
- Top Product
- Discover our top product BRAP Anticorps primaire
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- Indications d'application
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-BRAP antibody ABIN7451664.
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 12 months
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- Antigène
- BRAP (BRCA1 Associated Protein (BRAP))
- Autre désignation
- BRAP (BRAP Produits)
- Synonymes
- anticorps imp, anticorps MGC68778, anticorps zgc:92894, anticorps BRAP, anticorps BRAP2, anticorps IMP, anticorps RNF52, anticorps 3010002G07Rik, anticorps BRCA1 associated protein S homeolog, anticorps BRCA1 associated protein, anticorps BRCA1-associated protein, anticorps brca1-associated protein, anticorps brap.S, anticorps brap, anticorps BRAP, anticorps NAEGRDRAFT_81654, anticorps CC1G_00971, anticorps CpipJ_CPIJ003557, anticorps Tsp_05101, anticorps LOC100282389, anticorps Brap
- Sujet
- Background: BRCA1-associated protein (BRAP) negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. BRAP acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. BRAP may also act as a cytoplasmic retention protein with a role in regulating nuclear transport [taken from the Universal Protein Resource (UniProt) Q7Z569].
- ID gène
- 8315
- NCBI Accession
- NP_006759
- UniProt
- Q7Z569
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