HRS (HRS) (AA 350-400) anticorps

N° du produit ABIN7452346

Détail du produit

Antigène: HRS

Épitope: AA 350-400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunoprecipitation (IP)

Fonction: Rabbit anti-HRS Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 350 and 400

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-HRS antibody ABIN7450342.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détail du antigène

Antigène: HRS

Autre désignation: HRS (HRS Produits)

Synonymes: anticorps HRS, anticorps Hrs, anticorps Hgr, anticorps ZFYVE8, anticorps hepatocyte growth factor-regulated tyrosine kinase substrate, anticorps hepatoCyte growth factor receptor, anticorps HGF-regulated tyrosine kinase substrate, anticorps HGS, anticorps Hgs, anticorps Tsp_05936

Sujet: Background: Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) is an endosomal protein that participates in the trafficking and sorting of proteins to degradative or recycling pathways. HRS can bind ubiquitin directly and plays a key role in sorting ubiquitinated proteins to lysosomes. HRS has also been demonstrated to regulate protein sorting independent of its ubiquitin-binding motif.

ID gène: 9146

NCBI Accession: NP_004703

UniProt: O14964

Pathways: CXCR4-mediated Signaling Events, EGFR Downregulation