DUSP12 anticorps (AA 1-50)
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- Antigène Voir toutes DUSP12 Anticorps
- DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
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Épitope
- AA 1-50
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DUSP12 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Fonction
- Rabbit anti-DUSP12 Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogène
- Between AA 1 and 50
- Isotype
- IgG
- Top Product
- Discover our top product DUSP12 Anticorps primaire
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- Indications d'application
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IP: 20 μL/mg lysate
WB: 1:2,000 - 1:10,000
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 12 months
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- Antigène
- DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
- Autre désignation
- DUSP12 (DUSP12 Produits)
- Sujet
- Background: Dual specificity protein phosphatase 12 (DUSP12) is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP12 is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain [taken from NCBI Entrez Gene (Gene ID: 11266)].
- ID gène
- 11266
- UniProt
- Q9UNI6
- Pathways
- Regulation of Carbohydrate Metabolic Process
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