POLA2 anticorps (AA 448-498)

N° du produit ABIN7452745

Détail du produit anti-POLA2 anticorps

Antigène: POLA2 (Polymerase (DNA Directed), alpha 2 (70kD Subunit) (POLA2))

Épitope: AA 448-498

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLA2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-PolA2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 448 and 498

Isotype: IgG

Information d'application

Indications d'application:

IP: 5 - 15 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur POLA2

Antigène: POLA2 (Polymerase (DNA Directed), alpha 2 (70kD Subunit) (POLA2))

Autre désignation: PolA2 (POLA2 Produits)

Synonymes: anticorps DNA polymerase alpha 2, anticorps F12B7.19, anticorps F12B7_19, anticorps zgc:56124, anticorps zgc:77841, anticorps wu:fb48f05, anticorps AI573378, anticorps DNA polymerase alpha 2, accessory subunit, anticorps DNA polymerase alpha 2, anticorps polymerase (DNA directed), alpha 2, anticorps polymerase (DNA directed), alpha 2, accessory subunit L homeolog, anticorps polymerase (DNA directed), alpha 2, accessory subunit, anticorps POLA2, anticorps pola2, anticorps pola2.L, anticorps Pola2

Sujet: Background: DNA polymerase alpha is a four-subunit enzyme that exhibits DNA polymerase and primase activity. The four subunits of the heterotetrameric DNA pol alpha are A, B, C, and D. Subunit A displays the catalytic activity while the C and D subunits exhibit the primase activity. DNA polymerase (pol) alpha subunit B (PolA2) is the 70 kDa subunit that may serve to couple the DNA pol alpha-primase complex to the initiation/elongation machinery. DNA pol alpha is the only polymerase in eukaryotic cells that is capable of starting chains de novo.

ID gène: 23649

NCBI Accession: NP_002680

UniProt: Q14181

Pathways: Telomere Maintenance, Mitotic G1-G1/S Phases, DNA Replication, Protein targeting to Nucleus, Synthesis of DNA, SARS-CoV-2 Protein Interactome