C17ORF85 anticorps (AA 25-75)

N° du produit ABIN7452805

Détail du produit anti-C17ORF85 anticorps

Antigène: C17ORF85 (Chromosome 17 Open Reading Frame 85 (C17ORF85))

Épitope: AA 25-75

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C17ORF85 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-C17orf85 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 25 and 75

Isotype: IgG

Information d'application

Indications d'application:

IP: 50-100 μL/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur C17ORF85

Antigène: C17ORF85 (Chromosome 17 Open Reading Frame 85 (C17ORF85))

Autre désignation: C17orf85 (C17ORF85 Produits)

Synonymes: anticorps ELG, anticorps HSA277841, anticorps C130061O14Rik, anticorps C78393, anticorps nuclear cap binding subunit 3, anticorps nuclear cap binding subunit 3 L homeolog, anticorps NCBP3, anticorps Ncbp3, anticorps ncbp3.L

Sujet: Background: C17orf85 (NCBP3) associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. C17orf85 (NCBP3) serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with C17orf85 (NCBP3) does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the C17orf85 (NCBP3) activity is critical to inhibit virus growth. [taken from the Universal Protein Resource (UniProt) Q53F19].

ID gène: 55421

UniProt: Q53F19