ZNF207 anticorps (AA 428-478)

N° du produit ABIN7452845

Détail du produit anti-ZNF207 anticorps

Antigène: ZNF207 (Zinc Finger Protein 207 (ZNF207))

Épitope: AA 428-478

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF207 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-ZNF207 Antibody, Affinity Purified

Homologie: Orangutan

Purification: Affinity Purified

Immunogène: between AA 428 and 478

Isotype: IgG

Information d'application

Indications d'application:

IP: 50-100 μL/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur ZNF207

Antigène: ZNF207 (Zinc Finger Protein 207 (ZNF207))

Autre désignation: ZNF207 (ZNF207 Produits)

Synonymes: anticorps MGC116398, anticorps 4m77, anticorps MGC75627, anticorps ZNF207, anticorps Zfp207, anticorps wu:fb50g07, anticorps wu:fc17a09, anticorps wu:fc17a10, anticorps wu:fj12e11, anticorps zgc:56601, anticorps znf207, anticorps wu:fa03f07, anticorps wu:fb51h09, anticorps zgc:77832, anticorps zinc finger protein 207, anticorps zinc finger protein 207, b, anticorps zinc finger protein 207 S homeolog, anticorps zinc finger protein 207, a, anticorps Zfp207, anticorps znf207, anticorps ZNF207, anticorps znf207b, anticorps znf207.S, anticorps znf207a

Sujet: Background: ZNF207 is a kinetochore- and microtubule-binding protein that plays a key role in spindle assembly. ZNF207/BuGZ is mainly composed of disordered low-complexity regions and undergoes phase transition or coacervation to form temperature-dependent liquid droplets. Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by concentrating its building blocks. Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetochore loading of BUB3. Mechanisms by which BUB3 is protected are unclear: according to a first report, ZNF207/BuGZ may act by blocking ubiquitination and proteasomal degradation of BUB3 . According to another report, the stabilization is independent of the proteasome. [taken from the Universal Protein Resource (UniProt) O43670].

ID gène: 7756

UniProt: O43670