LMTK2 anticorps (AA 675-725)

N° du produit ABIN7453121

Détail du produit anti-LMTK2 anticorps

Antigène: LMTK2 (Lemur tyrosine Kinase 2 (LMTK2))

Épitope: AA 675-725

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LMTK2 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit anti-LMTK2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 675 and 725

Isotype: IgG

Information d'application

Indications d'application:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur LMTK2

Antigène: LMTK2 (Lemur tyrosine Kinase 2 (LMTK2))

Autre désignation: LMTK2 (LMTK2 Produits)

Sujet: Background: Lemur tyrosine kinase (LMTK2) belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. LMTK2 interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. LMTK2 is involved in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggest an essential role of this protein in spermatogeness [taken from NCBI Entrez Gene (Gene ID: 22853)].

ID gène: 22853

NCBI Accession: NP_055731

UniProt: Q8IWU2

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway