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Treslin anticorps (AA 975-1025)

Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7453283
  • Antigène Tous les produits Treslin
    Treslin
    Épitope
    • 1
    • 1
    • 1
    AA 975-1025
    Reactivité
    • 6
    • 3
    • 1
    • 1
    Humain
    Hôte
    • 6
    Lapin
    Clonalité
    • 6
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    Cet anticorp Treslin est non-conjugé
    Application
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Fonction
    Rabbit anti-Treslin Antibody, Affinity Purified
    Purification
    Affinity Purified
    Immunogène
    between AA 975 and 1025
    Isotype
    IgG
  • Indications d'application

    IP: Not recommended

    WB: 1:500 - 1:2,500

    Restrictions
    For Research Use only
  • Concentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    12 months
  • Antigène
    Treslin
    Abstract
    Treslin Produits
    Synonymes
    anticorps C15orf42, anticorps SLD3, anticorps Treslin, anticorps 5730590G19Rik, anticorps BC028450, anticorps Lrrk1, anticorps c15orf42, anticorps TOPBP1 interacting checkpoint and replication regulator, anticorps TopBP1-interacting, checkpoint, and replication regulator, anticorps TOPBP1-interacting checkpoint and replication regulator, anticorps TOPBP1-interacting checkpoint and replication regulator L homeolog, anticorps TICRR, anticorps ticrr, anticorps Ticrr, anticorps ticrr.L
    Sujet
    Background: Treslin is a regulator of DNA replication and S/M and G2/M checkpoints. Treslin regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Treslin is required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC) and for the prevention of mitotic entry after treatment with ionizing radiation [taken from the Universal Protein Resource (UniProt) Q7Z2Z1].
    ID gène
    90381
    NCBI Accession
    NP_689472
    UniProt
    Q7Z2Z1
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