PCNT anticorps (AA 175-225)

N° du produit ABIN7453380

Détail du produit anti-PCNT anticorps

Antigène: PCNT (Pericentrin (PCNT))

Épitope: AA 175-225

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCNT est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC)

Fonction: Rabbit anti-Pericentrin/Kendrin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 175 and 225

Isotype: IgG

Information d'application

Indications d'application:

ICC-IF: 1:1,000 - 1:5,000. Formaldehyde or Acetone fixation is recommended. Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PCNT

Antigène: PCNT (Pericentrin (PCNT))

Autre désignation: Pericentrin/Kendrin (PCNT Produits)

Synonymes: anticorps AKAP450, anticorps CG13459, anticorps CG18648, anticorps CG33957, anticorps CG6735, anticorps CP309, anticorps Cp309, anticorps D-PLP, anticorps DPLP, anticorps Dmel\\CG33957, anticorps Dplp, anticorps PACT, anticorps PLP, anticorps Plp, anticorps d-plp, anticorps dPLP, anticorps dplp, anticorps l(3)s2172, anticorps pPlp, anticorps KEN, anticorps MOPD2, anticorps PCN, anticorps PCNT2, anticorps PCNTB, anticorps PCTN2, anticorps SCKL4, anticorps DIP2A, anticorps AW476095, anticorps C86676, anticorps Pcnt2, anticorps kendrin, anticorps m239Asp, anticorps m275Asp, anticorps pericentrin, anticorps Pericentrin-like protein, anticorps pericentrin (kendrin), anticorps LOC100055203, anticorps Plp, anticorps PCNT, anticorps pcnt, anticorps Pcnt

Sujet: Background: Pericentrin (PCNT) is a large centrosomal protein that binds calmodulin and mediates assembly of the mitotic spindle apparatus. Depletion of PCNT has been shown to cause apoptosis and activation of the G2/M checkpoint. Recently, mutations in the pericentrin gene have been identified as the cause of primordial dwarfism type II (MOPDII) and Seckel syndrome. Additionally, in cells of Seckel syndrome patients, PCNT has been found to be important to the DNA damage response and ATR-dependent checkpoint signaling.

ID gène: 5116

NCBI Accession: NP_006022

UniProt: O95613

Pathways: Sensory Perception of Sound, M Phase, SARS-CoV-2 Protein Interactome