PELP1 anticorps (AA 1000-1050)

N° du produit ABIN7453550

Détail du produit anti-PELP1 anticorps

Antigène: PELP1 (Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))

Épitope: AA 1000-1050

Reactivité: Souris, Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PELP1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-PELP1/MNAR Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1000 and 1050

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PELP1

Antigène: PELP1 (Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))

Autre désignation: PELP1/MNAR (PELP1 Produits)

Synonymes: anticorps MNAR, anticorps P160, anticorps RGD1306320, anticorps 4930563C04Rik, anticorps proline, glutamate and leucine rich protein 1, anticorps proline, glutamate and leucine rich protein 1 L homeolog, anticorps proline, glutamic acid and leucine rich protein 1, anticorps PELP1, anticorps Pelp1, anticorps pelp1.L

Sujet: Background: PELP1/MNAR was identified as an SH2 domain interacting protein that interacts with Lck, c-Src, and other members of the Src kinase family. PELP1/MNAR appears to function as a general coregulator and interacts with multiple nuclear receptors and transcription factors. PELP1/MNAR has also been shown to participate in nongenomic signaling via an association with a multiprotein complex, the ""signalsome"" involving ERalpha, Src kinase, PI3K, SHC, and G-proteins. As a transcriptional coregulator and signaling protein, PELP/MNAR mediates a variety of cellular functions such as cell proliferation, apoptosis, differentiation, oncogenesis and metastasis.

ID gène: 27043

UniProt: Q8IZL8