INTS6 anticorps (AA 750-800)

N° du produit ABIN7453687

Détail du produit anti-INTS6 anticorps

Antigène: INTS6 (Integrator Complex Subunit 6 (INTS6))

Épitope: AA 750-800

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INTS6 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-DDX26/DICE1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 750 and 800

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur INTS6

Antigène: INTS6 (Integrator Complex Subunit 6 (INTS6))

Autre désignation: DDX26/DICE1 (INTS6 Produits)

Synonymes: anticorps DBI-1, anticorps DDX26, anticorps DDX26A, anticorps DICE1, anticorps HDB, anticorps INT6, anticorps Notchl2, anticorps EIF3-P48, anticorps EIF3S6, anticorps eIF3-p46, anticorps 2900075H24Rik, anticorps AI480962, anticorps Ddx26, anticorps Notch2l, anticorps LRRGT00024, anticorps ints6, anticorps zgc:63527, anticorps INTS6, anticorps ints6-b, anticorps Int6-A, anticorps dbi-1, anticorps ddx26, anticorps ddx26a, anticorps dice1, anticorps hdb, anticorps int6, anticorps ints6-a, anticorps notchl2, anticorps integrator complex subunit 6, anticorps eukaryotic translation initiation factor 3 subunit E, anticorps integrator complex subunit 6 like, anticorps integrator complex subunit 6 S homeolog, anticorps integrator complex subunit 6 L homeolog, anticorps INTS6, anticorps EIF3E, anticorps Ints6, anticorps ints6l, anticorps ints6, anticorps ints6.S, anticorps Tsp_09465, anticorps LOC100164318, anticorps ints6.L

Sujet: Background: DDX26/DICE1 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-His) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. RNA helicases play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX26/DICE1 is a subunit of the integrator complex involved in 3'-end processing of snRNAs. DDX26/DICE1 is implicated as a tumor suppressor, and its ectopic expression has been shown to inhibit tumor cell growth. Alternative names for DDX26/DICE1 include integrator complex subunit 6, Int6, protein deleted in cancer 1, protein DDX26, DBI-1, deleted in cancer 1, INTS6, DDX26A, HDB, Nochl2, and DKFZP434B105.

ID gène: 26512

NCBI Accession: NP_036273

UniProt: Q9UL03