FLII anticorps (AA 425-475)

N° du produit ABIN7453708

Détail du produit anti-FLII anticorps

Antigène: FLII (Flightless I Homolog (FLII))

Épitope: AA 425-475

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FLII est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-Flightless-1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 425 and 475

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur FLII

Antigène: FLII (Flightless I Homolog (FLII))

Autre désignation: Flightless-1 (FLII Produits)

Synonymes: anticorps FLI, anticorps FLIL, anticorps Fli1, anticorps 3632430F08Rik, anticorps Fliih, anticorps im:7141769, anticorps DKFZp459O043, anticorps flightless, anticorps FLII, actin remodeling protein, anticorps flightless I actin binding protein, anticorps protein flightless-1 homolog, anticorps FLII, actin remodeling protein S homeolog, anticorps Protein flightless-1 homolog, anticorps FLII, anticorps Flii, anticorps flii, anticorps LOC585336, anticorps LOC100640615, anticorps flii.S, anticorps fli-1

Sujet: Background: Flightless-1 is the human homolog of the drosophila flightless (fli1), a gene required for proper development of flight muscles and essential to embryonic development. It is a member of the gelsolin family of actin-binding proteins, and is highly conserved among vertebrates and invertebrates. The actin-remodeling activity of flightless-1 may have multiple roles in the cell. Studies in transgenic mice indicate a role in wound healing that may involve the regulation of cell migration and proliferation. Flightless-1 has also been found to be associated with complexes involved in transcriptional regulation. It associates with CARM1, a protein arginine methyltransferase, and may function as a nuclear receptor coactivator via this interaction. It has also been shown to associate with the BAF53a subunit of the SWI/SNF-like chromatin remodeling complexes.

ID gène: 2314

NCBI Accession: NP_002009

UniProt: Q13045